The core reasons for the physical defects of tablets are three categories: unsuitable material properties, improper process parameters and abnormal equipment status. Different defects (such as loose tablets, cracked tablets, sticking and so on) can be attributed to the problems in specific links.I.
Wet granulation combines powders with liquid binders (e.g., water/ethanol) to form granules, improving flowability and uniformity for tablet compression. It uses a high-shear mixer with a pot, agitator, and chopper to mix and cut the material. Key controls include binder amount (affects moisture), agitator speed (shear force), and chopper speed (particle size).
Last week, we exported one set fully automatic capsule filling machine model NJP-1200C to Greece, which includes size 0 and 00 molds, a water tank, a vacuum pump, a dust collector and other auxiliary devices. This customer is specilized in nutritional supplements and will use this machine to fill po
Mold punch adhesion refers to the phenomenon where a thin layer or a small portion of the tablet's surface is stuck to the punch of mold, resulting in rough and uneven surface or dents on the tablets.
1. Pressure ParametersMain Compression Pressure (Unit: kN)· Definition: Primary force applied by upper and lower punches to the material in the die cavity.· Impact:· Insufficient pressure → Low hardness, crumbling, or loose tablets.· Excessive pressure→ Hard tablets with delayed disintegrati
Blister packaging is an efficient, cost-effective, and protective solution for solid dosage forms. The manufacturing process involves five core steps: molding, filling, sealing, coding, and trimming. Each step requires precise control to ensure product quality and stability. Through advanced online
Hunan Innov Equipment Co., Ltd., established in 2014, specializes in the research and development, production, and global distribution of machinery and equipment.
